Product stability testing and compatibility testing

Donnington Laboratories offer real-time and accelerated product stability and compatibility testing services for developmental and investigative purposes, shelf life and PAO substantiation. Trials typically extend from 3 months to 3 years with tests at the various inspection points ranging from simple assessment of colour, odour and appearance to full physical testing (e.g. pH, viscosity, specific gravity, centrifuge testing), determination of sunscreen and preservative levels and pack integrity evaluation.

In determining the length of trial required, the basic rule of thumb is that shelf life doubles for each 10°C rise in storage temperature above ambient. Three months at 40°C thus equates to 12 months at ambient, 6 months at 40°C to 2 years at ambient and 9 months at 40°C to 3 years at ambient.

All commonly used storage conditions are offered ranging from: 5°C to 50°C plus the following humidity controlled conditions: 25°C/60%RH, 35°C/65%RH and 40°C/75%RH. Freeze-thaw cycling, natural sunlight and UV exposure testing facilities are also available.

Fully integrated product stability and compatibility testing

DLL offers a range of in-house stability and compatibility protocols which can be modified to meet clients’ requirements and are happy to adopt client-specified protocols, if required. We believe our charges offer exceptional value for money. Our stability and microbiology laboratories work closely together to provide a fully integrated product evaluation service which includes:

  • interim updates for longer term trials
  • prompt notification of adverse changes, accompanied by appropriate photographs
  • return of samples for client inspection
  • we also welcome visits by clients for sample inspection on-site

FURTHER INFORMATION ON PRICES AND SUBMISSION

OUR “STANDARD 5” STABILITY
Conditions: 5°C, 20°C, 40°C, NE window, freeze-thaw cycle (2w only)
Inspections: Initial, 2w, 4w, 8w, 12w
Tests: Colour, odour, appearance (COA) only £125.00
+ pH (start + end) + £40.00
+ Viscosity (start + end) + £88.00
+ pH (start, middle, end) + £65.00
+ Viscosity (start, middle, end) + £148.00
+ pH (all inspections) + £100.00
+ Viscosity (all inspections) + £250.00
OUR “STANDARD 6” STABILITY
Conditions: 5°C, 20°C, 30°C, 40°C, NE window, freeze-thaw cycle (2w only)
Inspections: Initial, 2w, 4w, 8w, 12w
Tests: Colour, odour, appearance (COA) only £150.00
+ pH (start + end) + £45.00
+ Viscosity (start + end) + £95.00
+ pH (start, middle, end) + £80.00
+ Viscosity (start, middle, end) + £170.00
+ pH (all inspections) + £115.00
+ Viscosity (all inspections) + £270.00
OUR “STANDARD 5” COMPATIBILITY
As “Standard 5” Stability, plus
Pack integrity (non-pump) + £125.00
Or
Pump integrity/functionality + £180.00
OUR “STANDARD 6”COMPATIBILITY
As “Standard 6” Stability, plus
Pack integrity (non-pump) + £150.00
Or
Pump integrity/functionality + £220.00
The above prices apply to single product submissions only. Discounts are available for multiple product submissions. Contact us for a quotation or to discuss your requirements in more detail.
All prices exclude VAT

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